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The keywords included trisomy 21, Down syndrome, oxidative stress, antioxidant capacity, lipid peroxidation, mitochondrial dysfunction, serine/threonine protein kinase, neurogenesis, antioxidant treatment, and clinical trials
For all other targets, in-house antibody conjugation of commercially available primary antibodies were prepared using the Maxpar X8 Antibody Labeling Kit (Standard BioTools, South San Francisco, CA, USA) per manufacturer instructions (Supplementary Table S14)
Maintains a youthful, radiant complexion by reducing fine lines and wrinkles
The mice were randomly divided into four groups (each containing at least five mice): a natural aging group, a natural aging + FOXO4-DRI group, a D-Gal group, and a D-Gal + FOXO4-DRI group
The adrenergic receptors are members of the G-protein coupled receptor (GPCR) family
The safety record is generally placebo-like, but several specific findings deserve attention
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