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Traditional medications, such as -blockers, carbonic anhydrase inhibitors, prostaglandin analogs, alpha-agonists, and cholinergic agonists, continue to play an essential role in managing IOP

For beginners, it's advisable to start at the lower end (2040 mcg/day) to assess tolerance and minimize side effects (Siddle, Growth Hormone & IGF Research )

Diabetes 65 , 27112723 (2016)

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Erhardt S, Lim CK, Linderholm KR, Janelidze S, Lindqvist D, Samuelsson M, Lundberg K, Postolache TT, Trskman-Bendz L, Guillemin GJ, Brundin L (2013) Connecting inflammation with glutamate agonism in suicidality

The post reports headache incidence of 5 to 8 percent in treatment arms versus 4 to 6 percent in placebo groups, which it calls a modest but meaningful difference