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LIPO-C is generally well-tolerated when administered correctly, but localised injection site reactions (redness, swelling, tenderness) occur in 1020% of patients during the first few weeks

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Peripherally administered liraglutide has recently been shown to gain access into certain areas of the brain with the majority entering the ARC and median eminence with smaller amounts in the PVN (Secher et al., 2014)