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The Precision Peptide Genetic Test ($298) analyzes genetic variants in your GLP-1 receptor, GIPR, FTO, and MC4R genes that influence how your body responds to different GLP-1 medications and dual-pathway therapies

While the mechanism is not yet proven, there is support for the idea that GLP-1 attenuates the ras homolog gene family, member A (RhoA)/Rho-associated protein kinase (ROCK) signaling pathway, whose activation is known to reduce levels of occludin, claudin-5, and zonula occludens-1 (ZO-1), as well as promote disruption of endothelial tight junctions

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