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Endorsements from celebrities such as Jennifer Aniston and Hugh Jackman, alongside recommendations from nutritionists and doctors, created a buzz around intermittent fasting as a hot health and wellness trend before the GLP-1 agonists captured the imagination of the world as dietary control in a pill

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Molecular dynamics simulations Molecular dynamics simulations have been performed using the AMBER ff19SB force field 57 and the solvent molecules were represented as OPC water molecules 58

A long-acting glucose-dependent insulinotropic polypeptide receptor agonist improves the Gastrointestinal tolerability of glucagon-like peptide-1 receptor agonist therapy