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"That's just sort of like a loading dose, to let your body get used to it." Lilly, which will also offer the $149 starting price under the Trump agreement, says additional doses of orforglipron will cost up to $399 if patients are paying cash

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Read the label carefully and don't duplicate the dose, since very high intakes can mask vitamin B12 deficiency

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Another patient on one of these drugs for weight loss told me that alcohol had lost its pull after years of failed attempts to quit