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First, semaglutide activates GLP-1 receptors in the brain, particularly in the hypothalamus, which reduces appetite and changes how you experience hunger
The effect lasted several hours, reducing hunger and food intake at subsequent meals
On one hand, its considered a hopeful remedy
Tibaduiza EC, Chen C, Beinborn M
This is where many people find their effective dose
"The Extracellular Surface of the GLP-1 Receptor Is a Molecular Trigger for Biased Agonism"
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