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doi:10.1124/jpet.108.149211 Raun K, Hansen BS, Johansen NL, et al
Consequently, research teams often rely on documented procedures that support repeatability, organization, and scientific consistency throughout the investigative process
Phase 3 TRIUMPH Program (Ongoing) - LIVER AS SECONDARY ENDPOINT Status: Currently ongoing, results expected 2026 TRIUMPH-4 (Completed December 2025): Primary endpoints: Weight loss + osteoarthritis pain Results: 28.7% weight loss at 68 weeks Liver outcomes: Secondary/exploratory endpoints TRIUMPH-2 (Ongoing, expected 2026): Weight loss in obesity + type 2 diabetes Liver outcomes: Secondary endpoints (liver enzymes, possibly imaging) Key Point: TRIUMPH Phase 3 trials are NOT primarily liver-focused
These treatments are generally combined with nutritional changes, movement, and behavioral coaching to support metabolic health goals
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