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86 These findings suggest that organism-level physiological states, including hormonal milieu, metabolic status, and systemic redox balance, can act as intrinsic determinants of the spatial boundaries and propagation threshold of ferroptotic injury

Inhibition of cystathionine--lyase leads to loss of glutathione and aggravation of mitochondrial dysfunction mediated by excitatory amino acid in the CNS

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This acts on bone marrow to stimulate erythropoiesis

That said, the animal research reveals several noteworthy cardiovascular effects

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