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"If taking medications that decrease appetite or insulin requirements, people with type 1 diabetes still must continue taking their long-acting insulin or using their insulin pump." Semaglutide, vomiting, and DKA: A case study In a 2023 case report, a person with type 1 arrived at an emergency room with ketoacidosis, after suffering nausea and vomiting attributed to taking Wegovy (semaglutide) prescribed by his endocrinologist for weight loss
No human half-life has been established
Drug/Laboratory Test Interactions Most antibiotics, methotrexate, and pyrimethamine invalidate folic acid and vitamin B12 diagnostic microbiological blood assays
Minnesota's own Department of Commerce has received advocacy pressure to mandate coverage parity for obesity pharmacotherapy, but no such mandate exists as of mid-2026
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