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GSTs are generally grouped into three classes based on their subcellular localization: membrane-bound microsomal, mitochondrial, and cytoplasmic (63)
Some tissues that might be particularly responsive to this signaling include muscle and bone cells
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Mitochondrial dysfunction in Redox imbalance is marked by decreased CoQ10 levels, reduced mitochondrial DNA content, and impaired electron transport chain activity, leading to excessive ROS production and decreased ATP synthesis
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