When administering a higher dose, the benefits should be weighed against the risks
Several factors can impair B12 absorption: Reduced stomach acid production (achlorhydria or hypochlorhydria), common in older adults and those taking proton pump inhibitors or H2-receptor antagonists long-term, impairs the release of B12 from food proteins Pernicious anaemia , an autoimmune condition destroying parietal cells and reducing intrinsic factor production, completely blocks the primary absorption pathway Gastrointestinal disorders including Crohn's disease, coeliac disease, or surgical removal of stomach or ileum sections directly damage absorption sites Metformin , commonly prescribed for type 2 diabetes, may reduce B12 absorption through unclear mechanisms
Frequently Asked Questions Can you take Vitamin B complex injections without a diagnosed deficiency
Because of the clinics discharge policy, at the end of my appointment I was required to be given intramuscular self-injection training by my doctors nurse
It acts as a coenzyme in various metabolic pathways and is involved in DNA synthesis and red blood cell production
Signs include itching, hives, trouble breathing, and swelling of the face, lips, or throat