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Because many of the sales of these medications are coming from off-label weight loss prescriptions, once orforglipron is approved -- even if only initially for type 2 diabetes -- we can expect demand and sales to be robust

By managing the dosage of GLP-1 medications and ensuring adequate protein consumption, patients can maintain or even increase their muscle mass while using these drugs

Longer diabetes duration correlated with older age, a higher proportion of females, a history of stroke, peripheral arterial disease, insulin use, and poorer kidney function