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Many cardiologists have recommended bariatric surgery but not usually the prescription medications due to concerns of cardiac and other toxicities, which should not be an issue with this medication. The data also show clinicians have a new opportunity to control obesity and its medical complications, including type 2 diabetes, according to Ken Fujioka, MD, former director of the Center for Weight Management and director of the Nutrition and Metabolic Research Center at Scripps Clinic San Diego

Comprehensive medical assessment before initiating treatment remains essential, as clinical trial populations never fully represent the diversity of health conditions encountered in practice

Seacat, A

2013 May;19(5):576-85

But rapid weight loss especially in the absence of strength training or adequate protein intakeoften comes at the cost of lean body mass

however, these outcomes did not remain statistically significant after adjustment for multiple testing