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By activating the PKA/CREB pathway, GLP-1RAs promote the expression of pro-survival genes such as Bcl-2 and JunB, thereby counteracting the pro-apoptotic signals of CHOP (Cunha et al., 2014, 2009)

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Furthermore, we revealed that the hydrophobic domain of ACTL6A is essential to the ACTL6A-GCLC-GSH synthesis-ferroptosis axis

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