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A faint, fleeting fishy scent that fades when the bottle is opened is often harmless and due to headspace volatiles, but a strong, persistent fishy smellespecially in liquids or with visual changes like cloudiness or sedimentis a sign of chemical degradation or microbial contamination and should be discarded
10.1007/s10989-017-9641-1 323 ZeinN.YassinF.EldeenE.ElshorbagyI
Phase 2 showed that participants who started at 4mg had nearly double the rate of gastrointestinal side effects compared to those who started at 2mg
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10.1007/s00425-012-1696-9 118 PantheeD
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