This approach has the potential to address multiple metabolic vectors underlying T2DM, obesity, and related comorbidities, such as non-alcoholic fatty liver disease, by targeting multiple pathways involved in glucose metabolism and appetite regulation
The semaglutide schedule starts at 0.25 mg weekly for four weeks and reaches the 2.4 mg maintenance dose after 16 weeks
68 RoumesH.DumontU.SanchezS.MazuelL.BlancJ.RaffardG.et al (2021)
It also has a mild testosterone-supporting effect in women and can be gently supportive of thyroid function
Recovery and Aftercare After receiving injection lipolysis, you can expect: Swelling (most common side effect) Redness and potential bruising Tenderness in the treated area Temporary numbness Gradual fat reduction over weeks Most patients return to normal activities immediately after treatment
Takeaways Given the concerns about retinopathy progression, internists may also seek input from optometrists on whether GLP-1/GIP agonists should be prescribed in patients with existing retinopathy