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On one hand, metabolites of glycyrrhizin enhance vascular contraction in response to pressor hormones such as angiotensin II, thereby increasing vascular tension

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However, in patients with a non-dipping pattern at baseline, the proportion of dippers for systolic/diastolic BP at 8 weeks of follow-up (36.5% vs

Subsequently, the released ferrous/iron ions will react with excess hydrogen peroxide in the cell to produce a Fenton-like reaction generating hydroxyl free radicals (OH), and induce ferroptosis of tumor cells [205]