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And, with the dismal results of the clinical trials, do we have any reason to believe that a GLP-1-targeted strategy might do better

Data were pooled for glucagon-like peptide 1 (GLP-1) receptor agonists and dipeptidyl-peptidase 4 (DPP-4) inhibitors in comparison with their respective controls and expressed as exposure-adjusted incidence rates

Diabetes (2004) 53(9):2397403