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Its effects on reducing corticotropin levels suggest involvement in stress-adaptive pathways, adding complexity to its pharmacological profile beyond simple sleep induction

10.1016/j.tips.2023.07.007 90 RyanS

There is pretty good evidence from previous studies that if you slow the rate of weight loss down, the body has more time to acclimate and youre less likely to get these symptoms, Lee said

For patients who struggle with constipation, increasing fiber intake or taking a daily fiber supplement helps