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Upregulation of CXCR4 is essential for the migration and survival of quiescent CML progenitor cells in the bone marrow microenvironment after Imatinib treatment

and Jeffrey Bland, PhD as they further explore this robust molecule and its vast implications for our health

This enables the drug to get quickly into the body without a reduction in the amount of drug

Collins R, Kantarjian HM, Kadia TM, Borthakur G, Konopleva M, Garcia-Manero G, Daver NG, Pemmaraju N, Jabbour E, Estrov Z, Ramachandran A, Paradela J, Pond B, Ravandi F, Vusirikala M, Patel PA, Levis MJ, Perl AE, Andreeff M , Cortes JE

Spectra were analysed using Agilent MassHunter Qualitative Analysis and Agilent MassHunter Profinder software by referencing to an internal library of compounds