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Improved mitochondrial function is also vital for healthy aging and disease prevention

PFIC8 PFIC8 is caused by variants in the KIF12 gene, encoding for a microtubule motor protein

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In addition, GLP-1 can reduce liver cholesterol accumulation by inhibiting SREBP2 and PCSK9, and reduce liver bile acid synthesis by weakening the negative feedback inhibition of bile acid after inhibiting FXR