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Disclosures Some study authors declared affiliations with biotech, pharmaceutical, and/or device companies

Its effect is modest, with weight losses of not more than 3% after 12 months, after which time, the weight is partially regained, even with continuing therapy.50 There are no studies that have analyzed the effect of orlistat in patients with obesity and PsO or HS

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Liraglutide is an older, widely studied GLP-1 medication

Anecdotally reported effects: Nausea, vivid dreams, and transient dizziness appear in community forums

5-10% for liraglutide) Beyond 12 months: Weight maintenance phase