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An umbrella review of 13 meta-analyses concluded that berberine did not significantly decrease body weight, BMI, or waist-to-hip ratio, though it had some lipid-lowering benefits
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These findings highlight the importance of optimal SUA control in preventing cardiovascular diseases
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Extending the findings from the UK cohort study, additional real-world data derived from the Taiwan National Health Insurance Databasewhich encompasses Asian populations characterized by lower gallstone prevalence, low-fat and high-fiber dietary patterns, and lower body mass indexalso documented an elevated risk of biliary-related diseases linked to GLP-1 RAs compared with SGLT-2 inhibitors [36]
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