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Patients who are administered local anesthetics may be at increased risk of developing methemoglobinemia when concurrently exposed to the following drugs, which could include other local anesthetics (Table 5)

Ketamine is a dissociative drug

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However, reaching optimal therapeutic response typically requires 12-20 weeks as your dose gradually increases according to FDA-approved titration schedules

The extracellular endogenous antioxidants generally include the transition metal binding proteins i.e

The most appropriate choice depends on your individual health factors, budget, and tolerance