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In cohort studies, combination therapy was associated with a lower risk of MACE (RR 0.56 [95% CI 0.43, 0.71] and the kidney composite endpoint (RR 0.48 [95% CI 0.32, 0.73] relative to SGLT2 inhibitor or GLP-1 RA monotherapy
Anatomical studies, albeit in mice, identified dense GLP-1R-expressing fibers surrounding VTA dopamine neurons 47
Ethics approval was obtained from the Clinic University Hospital of Valencia research ethics board (2022/164) with a waiver of informed consent
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The overproduction of ROS compromises the functional integrity of the endoplasmic reticulum for calcium release, allowing for the induction of cholestasis
Diabetes diagnoses contribute to MDM scoring in the number and complexity of problems addressed column
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