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The molecule was rationally designed by Eli Lilly scientists to simultaneously engage three G-protein-coupled receptors central to metabolic homeostasis: the glucose-dependent insulinotropic polypeptide (GIP) receptor, the glucagon-like peptide-1 (GLP-1) receptor, and the glucagon receptor

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Thats the finding from a study published in Frontiers Nutrition looking at the diets of this group

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In addition, another report demonstrated the reparative role of GLP-1RAs in MI via modulating sirtulin (SIRT)1/Parkin/mitophagy [74]