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If you have pernicious anemia, any kind of digestive condition, or you've had gastric surgery, your gut may not absorb B12 the way it should

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If response at 300mcg appears minimal after two weeks, increase to 400mcg

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It also repairs protective skin barrier proteins to improve skin firmness, elasticity, and clarity

Current British Society of Gastroenterology guidance suggests considering a baseline upper GI endoscopy with biopsies in adults aged 50 or over with confirmed pernicious anaemia to document autoimmune gastritis