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The treatment landscape for CKM changed dramatically when agents from several medication classes, originally developed as glucose-lowering therapies, were recognized to reduce the risk of multiple components of CKM syndrome

Exclusion criteria included: Pregnancy, lactation, severe cardiovascular disease, having other infections such as human immunodeficiency virus (HIV), history of taking L-carnitine supplement in the last month, requires intensive care units (ICU), patients with high and critical disease severity, taking anti-inflammatory drugs out of the patient's medication regimen and the patient's unwillingness to continue cooperating with investigators

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10.1126/science.2183352 37 ToppoS.FlohL.UrsiniF.VaninS.MaiorinoM

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