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Improvement in FEV1 was achieved in 75% of patients with the same combination of drugs when used with a nebulizer instead of the inhaler
E.MeadeJ
Inhalable myofibroblast targeting nanoparticles for synergistic treatment of pulmonary fibrosis
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For comparison, we treated cells with tunicamycin (TUN, a widely-used ER stress inducer) which did not alter phospho-GCN2 (T899), but reduced the mobility of PERK, indicative of its increased phosphorylation (Fig
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