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These hormones are secreted in response to food intake and causes a decrease in bone resorption ( GIP (secreted from enteroendocrine K-cells) and GLP-1 (secreted from L-cells) have been extensively studied with respect to their effects on glucose metabolism as mediators of the incretin effect: i.e., the enhanced insulin secretion which occurs when glucose is ingested orally compared to i.v
An unexpected change in direction occurred after the publication by Nissen and Wolski implicating rosiglitazone in adverse clinical outcome following meta-analysis
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2010 Sep;21(3):202-7
Here is a straight, evidence-based answer, so you can decide whether B12 shots make sense for you
Indian Journal of Endocrinology and Metabolism (2024) 9
