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Despite these findings, to our knowledge, there are no large population-based studies that have investigated the incidence of new-onset major cardiovascular events or clinically significant portal hypertension events in patients with MASLD who are receiving treatment with GLP-1 agonists for any indication

Shao SC, Kuo LT, Huang YT, Lai PC, Chi CC: Using Grading of Recommendations Assessment, Development, and Evaluation (GRADE) to rate the certainty of evidence of study outcomes from systematic reviews: a quick tutorial

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This stands in stark contrast to the average weight loss seen with GLP-1 medications , which often ranges from 10 to 20 percent of body weight depending on the specific drug and dose