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Insulin resistance is a hallmark feature of type 2 diabetes, closely related to H 2 O 2 /O levels [181]

Prolonged elevation of blood glucose, as well as related adverse metabolic features such as dyslipidemia and chronic inflammation, lead ultimately to a range of debilitating health issues such as, cardiovascular disease, peripheral neuropathy, diabetic ketoacidosis, diabetic retinopathy, and diabetic nephropathy

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