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Qualification typically requires a BMI of 30 or higher, or 27 or higher with weight-related conditions like type 2 diabetes or hypertension

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However, there are some important considerations: Delayed gastric emptying : Semaglutide significantly slows gastric emptying, which could potentially delay the absorption of oral medications like topiramate

Human clinical evidence was prioritized for synthesis, with preclinical evidence used to contextualize biologic plausibility