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Lastly, make sure your provider knows that youre taking tirzepatide before you undergo any surgeries or procedures that require sedation

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Side Effect Mitigation The primary motivation for microdosing is reducing adverse effects: Theoretical advantages: Lower peak concentrations reduce nausea intensity Gradual exposure allows GI adaptation Reduced gastroparesis severity Better maintenance of normal eating patterns 2

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Published in the New England Journal of Medicine, it enrolled 751 adults with obesity but without type 2 diabetes

Stand slowly when rising from sitting or lying down, and avoid rapid position changes that trigger vertigo