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This decline contributes to multiple hallmarks of aging including decreased muscle mass and strength, increased fat accumulation, reduced bone density, impaired cognitive function, and compromised immune system performance

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[10] [2] The medication also slows gastric emptying and acts on central appetite centers in the hypothalamus, leading to reduced caloric intake and subsequent weight loss

Constipation is underappreciated relative to nausea

I experienced improved energy and reduced fatigue, particularly during periods of caloric restriction

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