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Yes, with a clear dose-response relationship: 0.25 mg dose: 9-11% constipation rate 0.5 mg dose: 12-14% constipation rate 1.0 mg dose: 15-18% constipation rate 2.4 mg dose: 23-24% constipation rate The increase from 0.5 mg to 2.4 mg roughly doubles the constipation risk

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(And Why It Matters So Much) Before we dive into the 'how,' let's quickly solidify the 'what' and 'why.' Peptides, like the CJC 1295 / Ipamorelin 5mg/5mg blend we meticulously synthesize, are shipped in a lyophilized state

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Do not spray directly onto the lyophilised powder