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Some patients benefit from additional glucose-management interventions like dietary modification or increased physical activity

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Instruct patients to test ketone levels regularly

Clinical Applications: What Semaglutide Treats Originally, semaglutide received FDA approval for managing type 2 diabetes, where it helps reduce hemoglobin A1C (a marker of average blood sugar control) by 1-1.5 percentage points

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For example, a 2020 study found: Genetic predisposition to elevated serum IGF-1 levels was associated with higher risk of type 2 diabetes and coronary artery disease. The researchers note: Abnormal serum IGF-1 levels are associated with an increased risk of type 2 diabetes and cardiovascular diseasethe role of IGF-1 levels within the normal range in cardiometabolic disease remains unclear. 4