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Acetyl-L-carnitine (levacecarnine) in the treatment of diabetic neuropathy

Martinchik AN et al

10.1038/nm.2886 35

At the cellular level, B12 acts as a cofactor for two critical enzymatic reactions: Methionine synthase converts homocysteine to methionine, essential for DNA methylation and synthesis Methylmalonyl-CoA mutase involved in fatty acid metabolism and myelin production By restoring adequate B12 levels, injections enable normal red blood cell maturation in the bone marrow, correcting the megaloblastic anaemia

Each IC 50 curve is represented as the mean and SD of the independent experiments

Effects of Vitamin D supplementation on resolution of fever and cough in children with pulmonary tuberculosis: a randomized double-blind controlled trial in Indonesia