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NNMT has emerged as a target in metabolic disease and cancer research, with 5-Amino-1MQ as a primary pharmacological tool compound

2011 Oct 11;8(3):160-71.

All of this data has clinical relevance: Polonikov , studying 4 cases of moderate to severe COVID-19, found that while the three patients with high normal plasma glutathione levels recovered quickly, the one with low glutathione levels, high plasma ROSs and ROS / GSH ratio was suffering from the most severe disease and, at the time of publication, was still ill

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