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The disparity in coverage between the anti-diabetic and anti-obesity GLP-1s shows how payer behavior is driven by the perceived medical necessity of products by their intended use, not by the molecule itself
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Shao and colleagues discovered that GLP-1 administration restores the balance of inhibitory signaling by enhancing GABA release, thereby promoting RGC survival and improving visual function in early DR
Although abovementioned strategies provide means to improve brain targeting, none of them could complete brain region-specific delivery, which is crucial for treatment of brain disorders
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