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3.3.1 Plasma GSH Levels Pharmacokinetic evaluations indicate that SAG achieves higher plasma GSH exposure than equivalent doses of unmodified GSH, with preliminary data suggesting more favorable absorption kinetics

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MSC-Exos activate Nrf2/HO-1 expression via the GOT1/CCR2 signaling pathway to prevent ferroptosis, reduce inflammation in OA mice, and improve their performance, providing a potential treatment for OA and other orthopedic diseases