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The Journal of bone and joint surgery

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Outcome of SARS-CoV-2 infection is linked to MAIT cell activation and cytotoxicity

Put plainly, the off period is not there because the compound stops working it is there because no one can point to human data showing that running it indefinitely is safe, and a scheduled break is the honest way to respect that gap

Levels of urea in the blood, a waste product from the bodys use of protein that should be eliminated by the kidneys, also dropped as did weight gain, largely from retaining urine, which also can occur with kidney disease