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doi: 10.1530/JOE-11-0094

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Additionally, semaglutide affects appetite hormones like ghrelin, which influences not just hunger but also circadian rhythm and sleep qualityboth factors that directly impact daytime alertness

To avoid unwanted weight loss and the gastrointestinal side effects that come with GLP-1s, Kaufman typically starts patients out on one-tenth of the standard starting dose of 2.5 milligrams

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