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In cancer therapy, MOF-mediated chemodynamic therapy achieves ~ 29.9% doxorubicin loading with sustained Fenton-catalytic ROS generation

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In rats, the reported average was about 3.8 hours after IV dosing and 6.9 hours after oral dosing

Activation of these receptors triggers two complementary processes: it accelerates lipolysis (the breakdown of stored triglycerides into free fatty acids for energy) while simultaneously inhibiting lipogenesis (the conversion of glucose and other substrates into new fat stores)