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3,11,12,30 DPP-4 inhibitors have not been shown to cause weight gain or hypoglycemia unless used in combination with other antihyperglycemic agents, such as insulin or sulfonylureas

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More than 1 million nerve fibers within the optic nerve relay visual signals from the eyes to the visual parts of the brain, and damaged fibers can disrupt the crucial eye-brain connection, leading to blindness

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