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Front Pharmacol 15:1370264 Zhang SJ, Zhang YF, Bai XH, Zhou MQ, Zhang ZY, Zhang SX, Cao ZJ, Wang L, Ding SW, Zheng HJ (2024) Integrated network pharmacology analysis and experimental validation to elucidate the mechanism of acteoside in treating diabetic kidney disease

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Animal doses do not translate directly to humans

Retatrutide drives the deep metabolic effect, including the glucagon-mediated bump in energy expenditure that sets it apart from older incretin drugs