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Besides, some of our included trials involved participants with different comorbidities, like diabetes and non-alcoholic fatty liver disease, which might have an impact on treatment effect

Tirzepatide as Compared with Semaglutide for the Treatment of Obesity. The New England Journal of Medicine , vol

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For these reasons, the present review focuses primarily on obesity with and without BED, and BN is included only where necessary for mechanistic completeness, not as a clinical target condition