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Davies H, Bignell GR, Cox C, Stephens P, Edkins S et al (2002) Mutations of the BRAF gene in human cancer

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Furthermore, in streptozocin (STZ i.c.v) -induced AD rats (77) and APP/PS1 mice (78), DPP-4 inhibitors sitagliptin and saxagliptin were observed to have the ability to eliminate A accumulation, clear abnormal phosphorylation of tau, and improve brain mitochondrial dysfunction probably through activation of AMPK in neuronal cells (66)

Toxins now are well established to impair the ability of our mitochondria, the batteries in every cell, to create energy