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Mass Spectrometry Identity Confirmation Theoretical mass for the CHNOS free base is 5135.9 g/mol, and each released lot has to match that figure within tolerance by LC-MS before release
In addition, the isoprenyl group can react with cysteine thiol and bind to proteins, thus forming irreversible S -prenylation reactions such as farnesylation
Nature 551, 247250
Giangrandi et al., 2024)
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